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ScientificMatch

In date-matching sites, ScientificMatch.com is a site situated on matching people according to MHC-compatibilities. [1] Of note, Scientific Match is the first matching site to pioneer the method of having matchees send in samples (saliva) of their body composition, so to determine genetic compatibility in terms of immune system function of the potential resultant offsprint.

History
The site ScientificMatch.com (Alexa-rank: 1,011,265), motto: “the science of love”, was launched, in December of 2007, by American mechanical Engineer Eric Holzle. The site was conceived by Holzle, a long-time internet site dater, after watching a TV discussion on the findings of the sweaty T-shirt study.

Overview
By having singles send in saliva samples, the site facilitates a laboratory analysis of each person's immune system type and, using this data, claims to create optimized “physical chemistry” or "sexual chemistry" between people based on the sweaty T-shirt study, a pattern, discovered in 1995, which finds that people are most attracted to the smell of people who have the most-dissimilar immune system. [2]

MHC matching
The theory of desired dissimilar immune system matching can be quantified according to markers on a person’s major histocompatibility complex (MHC), a large gene region that controls the immune system response, and postulates that couples attracted to this type of scent owing to the result that a resultant child would create a more robust immune system, more defensive against a greater variety of pathogens.

In the mid 1970s, MHC-dissimilar tendency matching was shown to be the case for mice (and later for other animals such as fish) and in 1995 Swiss biologist Claus Wedekind, creator of the sweat T-shirt study, proved that the pattern holds for humans. [3] In this study, Wedekind had a group of female college students smell T-shirts that had been worn by male students for three nights, without deodorant, cologne or scented soaps. Overwhelmingly, the women preferred the odors of men with the most dissimilar MHCs to their own (see: adjacent video).

Pros/Cons
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References
1. ScientificMatch.com – homepage.
2. Physical chemistry defined – ScientificMatch.com
3. Wedekind, C. et al. (1995). "MHC-dependent preferences in humans." Proceedings of the Royal Society of London 260: 245-49.

External links
● Daubs, Katie. (2008). “Love: It’s all in the DNA, U.S. firm says.” (PDF). The Ottawa Citizen, Feb. 24.

Libb-Thims	Latest page update: made by Libb-Thims , Jul 24 2008, 2:13 PM EDT (about this update About This Update Moved from: Science-based dating sites - Libb-Thims No content added or deleted. - complete history)
	Keyword tags: scientific match ScientificMatch.com (edit keyword tags) More Info: links to this page